U-Life™ 50
Cream for Localised Hyperkeratosis

(Thickened skin)

Moisturising and exfoliating paste for specific areas of thickened, peeling skin.

Keratolytic effect: U-Life 50 achieved 92% psoriatic plaque clearance after 21 days use.*

Moisturising effect: U-Life 50 increased skin hydration levels by 111% after 15 days of use.†


U-Life 50 is a product of the U-Life range, a complete line of products with hydrating and keratolytic action for the management of dry, very dry, rough and cracked skin for specific areas of the body. U-Life 50 (50% Urea) cream for localised hyperkeratosis. Moisturising and exfoliating paste for specific areas of peeling skin thanks to a high concentration of:

  • Urea Concentration
    Urea 50% (exfoliating)
  • Additional specifically selected ingredients
    • Lanolin (emollient with moisturising effect)

The consistency of this product is not that of a cream but is a thick, granular paste.



Do not apply to inflamed or grazed skin. For external use only. Avoid contact with the eyes.


* Study conducted in 25 plaque psoriasis patients with visible and appreciable psoriatic plaques (hyperkeratotic components) for up to 21 days (if clearance of the plaques was reached before day 21 the use of the product could be stopped at that point). Clinical and ultrasound assessment of the plaques was conducted at  baseline and then after 7, 14 and 21 days. Clinical clearance of hyperkeratosis at day 21 was observed in 23 out of 25 plaques (92%), with nine (36%) and ten (40%) patients already reaching clear status respectively at day 7 and 14.

† Study conducted in 20 participants with thickened skin on their heels. Participants applied the product twice a day for 14 days. Evaluation of the skin hydration was conducted after 14 days with a Corneometer (skin hydration measurement device). At at day 15, a significant increase of hydration  levels (+111%) were observed.